Botulinum toxin is best known to clinicians as a deadly poison produced by the Clostridium botulinum bacterium. Only within the past 2 decades have clinical applications for this toxin surfaced. Originally, applicability was found for botulinum toxin in the treatment of strabismus; however, this single indication has now grown into many. Currently, the Food and Drug Administration (FDA) has approved botulinum toxin A for several indications, including blepharospasm, strabismus, cervical dystonia, chronic migraines, axillary hyperhidrosis, upper limb spasticity, urinary incontinence, and the aesthetic improvement of glabellar rhytides. The list of indications continues to grow, including off-label use of this product. See an example illustrated below.
Frontalis muscle injections.